Manufacturers Supply 1-Hydroxybenzotriazole /HOBT Anhydrous CAS 2592-95-2

English name: 1-Hydroxybenzotriazole
CAS number: 2592-95-2
Molecular formula: C6H5N3O
Molecular weight: 135.12
EINECS number: 219-989-7

1-Hydroxybenzotriazole (HOBT) is a common reagent used in organic chemistry, particularly in peptide synthesis and other reactions involving carboxylic acids and amines. HOBT, which stands for Hydroxybenzotriazole, is a chemical compound used in peptide synthesis and related organic chemistry reactions.HOBT is used to improve the efficiency of peptide coupling reactions. It functions as a peptide coupling reagent by activating the carboxylic acid group, making it more reactive and facilitating the formation of peptide bonds. The anhydrous form of HOBT is particularly important because it lacks water, which can interfere with peptide coupling reactions.

In peptide synthesis, the coupling of an amino acid with a carboxylic acid typically involves the use of a coupling agent like HOBT, a base, and a dehydrating agent to remove any water that may be generated during the reaction. This ensures that the peptide bond forms efficiently without side reactions.

Overall, 1-Hydroxybenzotriazole (HOBT) anhydrous is a valuable reagent in the field of organic chemistry, especially in the synthesis of peptides and related compounds. It helps improve reaction yields and reduce the formation of unwanted by-products.

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Product Range:
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