Manufacturer Supply Amino Acid Fmoc-Glu(OtBu)-OH In Stock CAS 71989-18-9

English name: Fmoc-L-glutamic acid 5-tert-butyl ester
CAS number: 71989-18-9
Molecular formula: C24H27NO6
Molecular weight: 425.47
EINECS number: 276-253-8

Fmoc-Glu(OtBu)-OH is a specific chemical compound used in peptide chemistry and solid-phase peptide synthesis. Let’s break down its structure:

Fmoc: This stands for Fluorenylmethoxycarbonyl, which is a commonly used protecting group in peptide synthesis. It is attached to the amino group (-NH2) of an amino acid to protect it from undesired reactions during peptide assembly.

Glu: This represents the amino acid glutamic acid. Glutamic acid is one of the 20 standard amino acids that make up proteins.

(OtBu): This is an abbreviation for tert-butyl ester, which is used to protect the carboxylic acid group (-COOH) of the glutamic acid.

So, Fmoc-Glu(OtBu)-OH is a molecule consisting of a glutamic acid derivative with the amino group protected by the Fmoc group and the carboxylic acid group protected by the (OtBu) ester. This compound is used as a building block in the synthesis of peptides, where amino acids are linked together in a specific sequence to create peptide chains. The protecting groups are added to control the reactions at each step of the synthesis and ensure the desired sequence is obtained. Once the peptide chain is complete, these protecting groups can be selectively removed to reveal the functional groups of the amino acids.

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