Reliable Factory Supply Top Quality TBTU CAS 125700-67-6 For Peptide Synthesis

English name: 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
CAS number: 125700-67-6
Molecular formula: C11H16BF4N5O
Molecular weight: 321.09
EINECS number: 603-087-9

Tert-Butylthiol-1H-benzotriazole-1-oxide (TBTU) is a chemical compound used in organic chemistry as a reagent for peptide synthesis and other amide bond-forming reactions. It is a coupling reagent that facilitates the reaction between carboxylic acids and amines to form amide bonds, a crucial step in peptide and protein synthesis. TBTU is known for its efficiency and is often used in solid-phase peptide synthesis.

It helps activate carboxylic acids, making them more reactive towards amine nucleophiles. This reactivity is essential for the formation of peptide bonds, which are the building blocks of proteins and peptides.

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